Dr. Muschler is an Orthopaedic Surgeon and Clinician-Scientist at the Cleveland Clinic.
His clinical practice consists of integrative complex adult reconstructive surgery, joint preservation, and bone and cartilage repair.
At the Cleveland Clinic, Dr. Muschler also leads the Regenerative Medicine Laboratory in the Department of Biomedical Engineering, which focuses on stem and progenitor cell biology, aging, tissue engineering and regenerative medicine, and has earned continuous federal funding for over 20 years. He has served as Vice Chair of Bioengineering (2004-2013); Director of the Orthopaedic Research Center (2005-2013), and as Vice Chair of the Orthopaedic and Rheumatologic Institute (2007-2013). He has served as Director of the Cleveland Clinic Joint Preservation Center since 2017.
Dr. Muschler has lead the development of several multi-institutional collaborative translational networks. He founded and led the Ohio-based Clinical Tissue Engineering Center (2005-2012), and served as the founding Co-Director of the Armed Forces Institute of Regenerative Medicine (AFIRM) (2008-2011), a national network funded by the Department of Defense and dedicated to the accelerated development of improved therapies which serve wounded warriors. He currently serves as Co-Chairman of the Committee on Orthopaedics and Musculoskeletal Cell Therapies within the International Society for Cellular Therapy (ISCT).
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Dr. Muschler is also the founding scientist of Cell X Technologies, Inc.
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Dr. Muschler earned his undergraduate degree in Chemistry at the University of Illinois in Champaign-Urbana, M.D. at Northwestern University, Orthopaedic Surgery residency at University of Texas Southwestern, Dallas, and completed fellowships at Memorial Sloan Kettering Cancer Center and the Hospital for Special Surgery in New York City.